Description
PALDA is an endogenous fatty acid dopamide that displays 'entourage' effects on endovanilloids NADA and anandamide. PALDA is inactive at TRPV1 and CB1 receptors (at concentrations up to 5 µM) and does not inhibit AMT or FAAH (IC:50:> 25 µM). PALDA additionally potentiates TRPV1-mediated effects of NADA and lowers EC:50:from ~ 90 to ~ 30 nM